Name: Dr Sam Newton Get his Email address here: samkofinewton@yahoo.com Telephone Number: +233 61 37304 Related links: Dr. Sam Newton of KHRC Congratulated.

BSC,MSC,MBChB,PhD(Epidemiology)

Background:

Dr Sam Newton is a Clinical Research Fellow at the Kintampo Health Research Centre. He completed medical school in 1993 with a BSc in Human Biology and an MBChB in medicine and surgery. After completing his housemanship at the Komfo Anokye Teaching hospital, he joined the Kintampo Health Research Centre in June 1996 as a clinician on the centre's first field trial the EPI plus study. It was a randomised double-blind, placebo-controlled, field trial that evaluated the safety and efficacy of high dose (200,000 IU) maternal vitamin A supplementation in the immediate post-partum period, given in addition to 4 small doses (25, 000 IU) delivered to the infant at the time they received their DPT/Polio immunizations.

He has carried out numerous field trials in malaria, iron and vitamin A as well as vaccine trials mainly in the area of polio, tetanus, hepatitis B and Haemophilus influenzae type b. In 2000 he was awarded a fellowship to undertake an MSc in Public Health in Developing Countries at the London School of Hygiene and Tropical Medicine, University of London and completed in 2001 when he returned to the centre.

In 2004 he was admitted to the London School of Hygiene and Tropical Medicine to do a PhD in Epidemiology as the first distance learning PhD student in Epidemiology at the school. His topic was "Randomised controlled trial assessing the impact of vitamin A supplementation on the immune responses to hepatitis B and Haemophilus influenza type b among young infants in Ghana". He completed in 2007 after his thesis had been adjudged to be excellent by his two examiners.

Dr Sam Newton has published extensively in international peer review journals mainly in the area of micronutrients, vaccines and research ethics. He has attended several international conferences both as a participant and as a presenter.

Interest:

His main interest is in combining clinical practice with public health and ethics and in trying to identify solutions to the public health problems, which we face in developing countries.

Selected Publications

1. Sam Newton, Seth Owusu-Agyei, Suzanne Filteaub, Thomas Gyana, Betty R. Kirkwood.
   Vitamin A supplements are well tolerated with the pentavalent vaccine. Vaccine. 15 September 2008
2. Sam Newton and John Appiah Poku J,
   Opinion of researchers based in the UK on recruiting subjects from developing countries into randomized controlled trials.Developing World Bioethics 2007, Dec (3) 149-156.
3. Sam Newton and John Appiah Poku,
   Perspectives of researchers on obtaining informed consent in developing countries. Developing World Bioethics.2007 April (1) 19-24
4. Newton S, Owusu-Agyei S.
   Need to worry: wrong vitamin A doses reported! Vaccine. 2007Jun 6;25(23):4514. Epub 2007 Jan 16.
5. Newton S, Owusu-Agyei S, Kirkwood B
   Is there any monitoring of the quality of vitamin A capsules used in supplementation programs? Am J Clin Nutr. 2007 Oct;86(4):1254.
6. Newton S, Owusu-Agyei S, Ampofo W, Zandoh C, Adjuik M, Adjei G, Tchum S, Filteau S, Kirkwood BR
   Vitamin A supplementation enhances infants' immune responses to hepatitis B vaccine but does not affect responses to Haemophilus influenzae type b vaccine. J Nutr. 2007 May;137(5):1272-7.
7. Tchum, S. K., Tanumihardjo, S. A., Newton S., de Benoist, B., Owusu-Agyei, S., Arthur, F. K. N., Tetteh, A.
   Evaluation of vitamin A supplementation regimens in Ghanaian postpartum mothers using the modified-relative-dose-response test. Am J Clin Nutr Vol.84, No.6 1344-1349, December 2006.
8. Zlotkin S, Schauer C, Owusu-Agyei S, Wolfson J, Tondeur MC, Asante KP, Newton S, Serfass RE, Sharieff W.
   Demonstrating zinc and iron bioavailability from intrinsically labeled microencapsulated ferrous fumarate and zinc gluconate Sprinkles in young children. J Nutr. 2006 Apr;136(4):920-5.
9. Newton S, Cousens S, Owusu-Agyei S, Filteau S, Stanley C, Linsell L et al.
   Vitamin a supplementation does not affect infants' immune responses to polio and tetanus vaccines. J Nutr 2005; 135(11):2669-2673.
10. Harold C. Furr, Michael Green, Marjorie Haskell, Najat Mokhtar, Penepole Nestel, Sam Newton, Judy Ribaya-Mercado, Guangwen Tang, Sherry Tanumihardjo, Emorn Wasantwisut.
    Stable Isotope Dilution Techniques for Assessing Vitamin A status and Bioefficacy of Provitamin A Carotenoids in Humans Public Health Nutrition 2005.8(6):596-607
11. Tondeur WC, Schauer C, Christofides AL, Asante KP, Newton S, Serfass RE et al.
    Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with different iron and hematologic status by using a dual-stable-isotope method. Am J Clin Nutr 2004; 80(5):1436-1444.
12. M. Tondeur, S. Zlotkin, C. Schauer, S Newton, S Owusu-Agyei: Departments of Paediatrics, Nutritional Sciences, and Centre for International Health, University of Toronto; The Hospital for Sick Children, Research Institute, Canada; The Kintampo Health Research Centre Health Research Unit, Ministry of Health, Ghana.
    Iron Absorption from Intrinsically Labelled Microencapsulated Ferrous Fumarate (SPRINKLES) in Anemic & Non-Anemic Infants: Presented at INACG, 2003 in Marrakesh, Morocco